San Francisco 49ers star tight end George Kittle missed his second straight practice on Friday as ESPN insider Adam Schefter ...

The San Francisco 49ers certainly have had some bad luck so far this season and are dealing with some high-profile injuries.

The Niners will perhaps be without arguably their three most important offensive weapons, sidelined stars Christian McCaffrey ...

Brown and Odum allowed Justin Jefferson to get behind them for a 97-yard touchdown pass from Sam Darnold. Both are considered ...

Here’s a list of the most significant players dealing with injuries and their latest statuses ahead of Week 3. Quarterbacks .

An oblique injury has kept Seattle Seahawks running back Kenneth Walker III out of the lineup. He missed their Week 2 win ...

The NFC North is one of only two divisions without a winless team through two weeks of the NFL season. Here are the latest On SI NFC North pow ...

Throughout an electric start to his NFL career, San Francisco 49ers quarterback Brock Purdy has seen caveats consistently ...

On Football analyzes the biggest topics in the NFL from week to week. For more On Football analysis, head here. ___ The next ...

The 49ers’ offensive line hasn’t been the strongest in pass protection so far this season. Starting right tackle Colton McKivitz is typically at the forefront o ...