Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

Lenyn Sosa hit a tying two-run homer with two outs in the ninth inning, but the Chicago White Sox lost their 118th game when ...

The Chicago White Sox staged a two-out rally in the 9th but fell to the San Diego Padres 3-2 in 10 on Friday. The Sox are ...

As the defeats continue to mount, the White Sox have joined the discussion of the most infamous baseball teams of all time.

The Chicago White Sox (36-117) kick off a three-game series on Saturday against the San Diego Padres (87-66). The matchup ...

At PETCO Park on Friday, the San Diego Padres (87-66) begin a three-game series versus the Chicago White Sox (36-117), at ...

Preview the Sept. 20 matchup between the San Diego Padres and Chicago White Sox with odds over/under, game spread, betting ...

Oddsmakers have listed player props for Jurickson Profar, Andrew Vaughn and others when the San Diego Padres host the Chicago ...

The Cubs are closing out the season with 10 of their final 13 games at Wrigley Field, while the White Sox have a tall task ...

What to look for from the top San Diego Padres and Chicago White Sox players and how to watch the game as they face off on ...

Preview the Padres vs. White Sox game today, with score predictions, stats, starting pitchers and game information.

As the Chicago White Sox look to avoid setting a new modern-era MLB record for losses in a season, the knives have come out ...